Vitamin A

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Vitamin A is a fat-soluble vitamin that is naturally present in many of the foods we eat. Retinol is the primary form of vitamin A in humans. This test measures the level of retinol in the blood.

Vitamin A is an essential nutrient required for healthy vision and skin, bone formation, immune system function, and reproduction. It is required to produce photoreceptors in the eyes and to maintain the lining of the surface of the eyes and other mucous membranes. A lack of vitamin A can affect night vision, cause eye damage, and in severe cases, lead to blindness. Too much vitamin A can be toxic, causing a range of symptoms, and sometimes leading to birth defects.

The body cannot make vitamin A and must rely on dietary sources of vitamin A. Meat sources provide vitamin A (as retinol), while vegetable and fruit sources provide carotene (a substance that can be converted into vitamin A by the liver). Vitamin A is stored in the liver and fat tissues (it is fat-soluble), and healthy adults may have as much as a year?s worth stored. The body maintains a relatively stable level in the blood through a feedback system that releases vitamin A from storage as needed and increases or decreases the efficiency of dietary vitamin A absorption.

Deficiencies in vitamin A are rare in the United States, but they are a major health problem in as many as half of all countries, especially in resource-poor nations where high numbers of people have limited diets, according to the World Health Organization (WHO). One of the first signs of vitamin A deficiency is night blindness. Young children and pregnant women are most commonly affected, say the WHO.

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