Beta 2 Glycoprotein IgG

1,001.00

Beta-2 glycoprotein 1 antibody is an autoantibody that is associated with inappropriate blood clotting. This test detects and measures beta-2 glycoprotein 1 antibodies in the blood.

Beta-2 glycoprotein antibody is considered one of the primary autoantibodies called antiphospholipid antibodies that mistakenly target the body?s own lipid-proteins (phospholipids) found in the outermost layer of cells (cell membranes) and platelets. This test is often ordered along with tests for other antiphospholipid antibodies, including cardiolipin antibody and lupus anticoagulant.

Antiphospholipid antibodies interfere with the body?s blood clotting process in a way that is not fully understood yet. They increase the risk of developing inappropriate blood clots (thrombi) in both arteries and veins.

Antiphospholipid antibodies most frequently develop in people with the autoimmune disorder called antiphospholipid syndrome (APS). This condition is associated with widespread blood clots (thrombotic episodes), a low platelet count (thrombocytopenia), or with pregnancy complications such as pre-eclampsia and recurrent miscarriages, especially in the second and third trimesters.

Also, some people with autoimmune disorders such as lupus (systemic lupus erythematosus, SLE) may begin to produce one or more of these autoantibodies, which can put them at risk of forming blood clots in blood vessels.

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